Pakistan Pharma Begins Domestic Production of GLP-1 Weight Loss Drugs

Several Pakistani pharmaceutical companies have started domestic production of generic versions of GLP-1 (Glucagon-Like Peptide-1) drugs Ozempic/Wegovy (Semaglutide) and Mounjaro/Zeptide (Tirzepatide). Priced significantly lower than the branded imports, these domestically manufactured generic drugs will increase Pakistanis' access and affordability to address the obesity crisis in the country, resulting in lower disease burdens and improved life quality and longer life expectancy. Obesity causes diabetes, hypertension, heart disease and other non-communicable diseases (NCD) which are now among the leading causes of death in Pakistan. 

Pakistan Pharmaceutical Companies

BF Biosciences, Ferozsons, Getz Pharma and GD Searle Co are among the leading pharma producers of both injectable and pill versions of the GLP-1 and GIP drugs in Pakistan.  Over the last few years, these drugs have revolutionized treatment of diabetes and obesity. Now, Pakistani pharmaceutical companies have begun manufacturing biosimilar versions of these therapies locally, marking a major milestone in access and affordability. Biosimilars are biologic medicines developed to match the safety, efficacy, and quality of their international counterparts, approved only after rigorous regulatory evaluation, according to Pakistani media reports

Obesity Risk Among Men. Source: World Obesity Atlas

The obesity crisis has become a global health emergency with over a billion people living with obesity in the world, creating global opportunities for weight-loss drugmakers. Rapidly rising rates of obesity in adults and children are being blamed on factors like processed foods, sedentary lifestyles, and stress, leading to serious conditions like diabetes, heart disease, certain cancers, and huge healthcare costs, requiring multifaceted solutions including policy changes, better nutrition, and integrated healthcare. 

Obesity Risk Among Women. Source: World Obesity Atlas

Pakistani drugmakers are planning to export these weight-loss and diabetes drugs in the near future.  Over a dozen pharma companies are upgrading factories with a total investment of more than $500 million to ensure their medications and factories are compliant with overseas regulations, said Javed Ghulam Mohammad, chief executive officer at Martin Dow Group. His company is a member of the Pakistan Pharmaceutical Manufacturers Association, which is backing the effort. The sector’s push comes as the nation looks to increase overall exports to lift the economy.

The country's drug exports have increased the most in two decades in the fiscal year ending in June, 2025, growing 34% to $457 million, according to the association. Pharmaceutical shipments have the potential to reach $5 billion in eight years if the overseas push is successful, Mohammad said. That would make pharmaceuticals among Pakistan’s largest product exports, according to Bloomberg

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  • Riaz Haq

    AI Overview
    Mounjaro Price in Pakistan (2025-2026) | Cost per Dose
    GLP-1s (Glucagon-like Peptide-1 Receptor Agonists) like Semaglutide (Ozempic) and Liraglutide are used in Pakistan primarily for Type 2 diabetes, showing significant benefits for blood sugar (HbA1c) and weight loss, with local studies confirming effectiveness and good tolerability, despite initial nausea/bloating. While demand surges for weight loss (an unapproved use), the Drug Regulatory Authority of Pakistan (DRAP) has issued warnings about fake versions circulating online, emphasizing prescription-only use for quality and safety. 
    Key GLP-1s Available in Pakistan:
    • Semaglutide: Highly effective for diabetes and weight loss, with local studies showing good results and patient satisfaction.
    • Liraglutide: Available since 2016, used for diabetes.
    • Dulaglutide: Available since 2018, often preferred for fewer injections (once weekly).
    • Combination Therapies: Liraglutide with Insulin Degludec also available. 
    Benefits Beyond Glucose Control:
    • Weight reduction.
    • Improved cholesterol/blood pressure.
    • Cardiovascular protection. 
    Safety & Availability Concerns:
    • Falsified Products: DRAP alerted about fake GLP-1s online due to high demand.
    • Prescription Needed: These are prescription-only medicines, often misused for unapproved weight loss.
    • Side Effects: Common but mild: nausea, bloating, constipation, usually improve over time. 
    Local Research & Trends:
    • Studies from Karachi and other centers confirm GLP-1s' efficacy for diabetes and weight in Pakistani patients.
    • Demand for both diabetes and weight management is high, prompting investment in local manufacturing (like Semaglutide).
    • Focus on education to counter misinformation, especially regarding weight loss uses. 

  • Riaz Haq

    AI Overview
    Eating ultra-processed food can make you prone to 32 ...
    Ultra-processed foods (UPFs) like biscuits, chips, sugary drinks, and instant noodles are a growing concern in Pakistan, especially in urban areas, fueling rising obesity, diabetes, and heart disease, with government initiatives proposing taxes and trans-fat bans to curb consumption, though affordability and access remain challenges for low-income families. Consumption is increasing due to urbanization and convenience, but biscuits and sweetened drinks are leading UPF sources, prompting calls for stronger food policies to address the public health threat.
    Common UPFs in Pakistan
    Biscuits & Packaged Snacks: A very common source of UPFs, often high in sugar, salt, and unhealthy fats.
    Sweetened Beverages: Soft drinks and juices contribute significantly to sugar intake.
    Instant Noodles & Processed Breads: Budget-friendly options, especially for lower-income families.
    Processed Meats & Sugary Snacks: Also contribute to the rising UPF intake.
    Why Consumption is Rising
    Urbanization: Increased availability and exposure to convenience foods.
    Time Constraints: Busy lifestyles lead to reliance on quick, processed options.
    Affordability/Accessibility: Budget-friendly UPFs become substitutes for fresh foods, though high-income groups also access premium UPFs.
    Globalization: Western eating habits influence choices, particularly among youth.
    Health Impacts
    Major contributor to Pakistan's crisis of obesity, diabetes, and cardiovascular diseases.
    High in sugar, sodium, and unhealthy fats, altering nutrient content and increasing health risks.
    Policy Responses
    Trans-Fat Ban: Pakistan adopted a national standard in 2025 to eliminate industrially produced trans-fats (iTFAs) by limiting them to less than 2% of total fat.
    Proposed Health Taxes: The Ministry of Health has proposed a 20% health tax on UPFs and beverages to discourage consumption and fund healthcare.
    Challenges
    Affordability: Taxes may disproportionately affect low-income families who rely on these affordable options.
    Industry Obstruction: Food producers often resist health-focused reforms.

  • Riaz Haq

    Highnoon Laboratories Limited holds groundbreaking ceremony for project - FORCE, the first FDA/EU-compliant facility in Pakistan - Profit by Pakistan Today
    Sheikhupura, January 22, 2026 — Highnoon Laboratories Limited marked a significant milestone with the groundbreaking ceremony of Project FORCE, its greenfield manufacturing expansion initiative, held at the Special Economic Zone, Quaid-e-Azam Business Park, Sheikhupura.
     

    Project FORCE is a strategic investment aimed at establishing a world-class, efficient, and globally compliant pharmaceutical manufacturing facility in Pakistan. The new facility is designed to strengthen Highnoon’s manufacturing footprint, support future growth ambitions and enhance the Company’s ability to serve both domestic and international markets.